Version 3.0
Date revised: 4/26/2019
SAFETY DATA SHEET
Conforms to regulation (EC) no. EU 453/2010
SECTION 1 - IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
1.1 Product Identifier
1.2 Relevant Identified Uses of the Substance/Mixture and Uses Advised Against
Investigational research by professional users
1.3 Details of the Supplier of the Safety Data Sheet
| Manufacturer National Diagnostics 305 Patton Drive Atlanta, GA 30036 (404) 699-2121 (800) 526-3867 info@nationaldiagnostics.com |
1.4 Emergency Telephone Number
ChemTel Inc.
Contract number MIS8894340
1-800 255-3924 (United States, Canada, Puerto Rico & US Virgin Islands)
01-800-099-0731 (Mexico)
400-120-0751 (China)
000-800-100-4086 (India)
1-300-954-583 (Australia)
0-800-591-6042 (Brazil)
+1-813-255-3924 (All other regions)
SECTION 2 - HAZARDS IDENTIFICATION
2.1 Classification of the Substance or Mixture
Not a hazardous substance or mixture according to regulation (EC) No. 1272/2008.
2.2 Label Elements
This product has no labeling elements associated with EC directives or respective national laws.
2.3 Other Hazards
None found.
SECTION 3 - COMPOSITION/INFORMATION ON INGREDIENTS
3.2 Mixture
Chemical Names/Description
Phosphate buffer containing additional proprietary electrolyte blend
Component List
| Component | % Comp. | CAS # | EC # | 1278/2008 Classification |
|---|---|---|---|---|
| Sodium/Potassium Phosphate Buffer | 80-90 | 7778-78-0 | 231-913-4 | N.A. |
| Proprietary Electrolyte | 10-20 | N.A. |
SECTION 4 - FIRST AID MEASURES
4.1 Description of First Aid Measures
Inhalation
Remove to fresh air. Get medical attention for any breathing difficulty.
Ingestion
If swallowed, give several glasses of water to drink to dilute. If large amounts were swallowed or symptoms occur, get medical advice. Never give anything by mouth to an unconscious person.
Skin
Wash exposed area with soap and water. Get medical advice if irritation develops.
Eyes
Wash thoroughly with running water. Get medical advice if irritation develops.
4.2 Most Important Symptoms and Effects, Both Acute and Delayed
Inhalation
Sodium/Potassium Phosphate Buffer:
Not expected to be a health hazard by inhalation.
Proprietary Electrolyte:
No data
Ingestion
Sodium/Potassium Phosphate Buffer:
Symptoms may include vomiting, lethargy, diarrhea, blood chemistry effects, cardiac effects and central nervous system effects.
Proprietary Electrolyte:
No data
Skin
Sodium/Potassium Phosphate Buffer:
No adverse effects expected.
Proprietary Electrolyte:
No data
Eyes
Sodium/Potassium Phosphate Buffer:
Pain and redness.
Proprietary Electrolyte:
No data
4.3 Indication of Any Immediate Medical Attention and Special Treatment Needed
Unknown/not applicable
SECTION 5 - FIRE FIGHTING MEASURES
5.1 Extinguishing media
Use media appropriate to the primary cause of fire.
5.2 Special Hazards Arising from the Substance/Mixture
Hazardous Combustion Products
N.A.
Hazardous Decomposition Products
Phosphorus oxides may form when heated to decomposition.
Hazardous Polymerization
Will not occur under normal conditions of use (See Sections 10.4 & 10.5).
5.3 Advice for Firefighters
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.
5.4 Further Information
No data available.
SECTION 6 - ACCIDENTAL RELEASE MEASURES
6.1 Personal Precautions
Wear appropriate protective equipment as specified in Section 8.
6.2 Environmental Precautions
Prevent discharge into the environment. Dike spills and stop leakage where practical. Do not allow material to enter drains.
6.3 Methods and Materials for Containment and Cleaning Up
Contain and clean up spill immediately, prevent from entering floor drains. Contain liquids using absorbents. Shovel all spill materials into disposal drum. Scrub spill area with detergent, flush with copious amounts of water.
6.4 References to Other Sections
For disposal information see Section 13. For protective clothing and equipment see Section 8.
SECTION 7 - HANDLING AND STORAGE
7.1 Precautions for Safe Handling
Avoid contact and inhalation. Do not get in eyes, on skin, on clothing. Wash thoroughly after handling.
7.2 Conditions for Safe Storage (including any incompatibles)
Keep in a tightly closed container, stored in a cooled, dry, ventilated area.
Incompatibles
Sodium/Potassium Phosphate Buffer:
No incompatibility data found.
Proprietary Electrolyte:
No incompatibility data found.
7.3 Specific End Uses
Investigational research by professional users
SECTION 8 - EXPOSURE CONTROLS/PERSONAL PRECAUTIONS
8.1 Control Parameters
Component: Sodium/Potassium Phosphate Buffer
ACGIH Threshold Limit Value (TLV):
10 mg/m3 total dust
OSHA Permissable Exposure Limit (PEL):
15 mg/m3 total dust
Component: Proprietary Electrolyte
ACGIH Threshold Limit Value (TLV):
none established
OSHA Permissable Exposure Limit (PEL):
None established
8.2 Exposure Controls
Engineering Controls
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source.
Respiratory Protection
For conditions of use where exposure to the dust or mist is apparent, a full-face dust/mist respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Eye Protection
Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Skin Protection
Wear protective gloves and clean body covering clothing.
SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
9.1 Information on Basic Physical & Chemical Properties
| a. Appearance | Crystalline solid | b. Odor | None |
| c. Odor Threshold | N.A. | d. pH | N.A. |
| e. Melting/Freezing Point (oC) | N.A. | f. Boiling point (oC) | N.A. |
| g. Flash Point (oC) | N.A. | h. Evaporation Rate | N.A. |
| i. Flammability | N.A. | j. Upper/Lower Flammability or Explosive Limits | N.A. |
| k. Vapor Pressure | N.A. | l. Vapor Density (Air = 1) | N.A. |
| m. Relative Density | 1.0 | n. Water Solubility | Soluble |
| o. Partition Coefficient n-octanol/water | Mixture | p. Autoignition Temperature (oC) | N.A. |
| q. Decomposition Temperature (oC) | Not applicable. | r. Viscosity | No data available. |
| s. Explosive Properties | N.A. | t. Oxidizing Properties | Not an oxidizer |
SECTION 10 - STABILITY AND REACTIVITY
10.1 Reactivity
Not reactive under normal conditions of use.
10.2 Chemical Stability
Stable under recommended conditions of use and storage
10.3 Possibility of Hazardous Reactions
Will not occur under normal conditions of use (See Sections 10.4 & 10.5).
10.4 Conditions to Avoid
No information found.
10.5 Incompatible Materials
Sodium/Potassium Phosphate Buffer:
No incompatibility data found.
Proprietary Electrolyte:
No incompatibility data found.
10.6 Hazardous Decomposition Products
Phosphorus oxides may form when heated to decomposition.
SECTION 11 - TOXICOLOGICAL INFORMATION
Product LD50 Values
Oral Rat LD50 (mg/kg)
No data
Dermal Rabbit LD50 (mg/kg)
No data
Component Cancer List Status
| NTP Carcinogen | |||
| Known | Anticipated | IARC Category | |
|---|---|---|---|
| Sodium/Potassium Phosphate Buffer | No | No | None |
| Proprietary Electrolyte | No data | N.A. | No data |
Potential Health Effects
Inhalation
Sodium/Potassium Phosphate Buffer
Not expected to be a health hazard by inhalation.
Proprietary Electrolyte
No data
Ingestion
Sodium/Potassium Phosphate Buffer
Phosphates are slowly and incompletely absorbed when ingested, and seldom result in systematic effects. Some adverse health effects have occurred. The toxicity of phosphates is because of their ability to sequester calcium. Acute potassium intoxication by mouth is rare because large single doses usually induce vomiting and because in the absence of pre-existing kidney damage, potassium is rapidly excreted. Potassium poisoning can result in heart effects.
Proprietary Electrolyte
No data
Skin
Sodium/Potassium Phosphate Buffer
No adverse effects expected.
Proprietary Electrolyte
No data
Eyes
Sodium/Potassium Phosphate Buffer
No adverse effects expected but may cause mechanical irritation.
Proprietary Electrolyte
No data
Carcinogenicity
Sodium/Potassium Phosphate Buffer
Not listed as a known or anticipated carcinogen by NTP or IARC.
Proprietary Electrolyte
No information available
Mutagenicity
Sodium/Potassium Phosphate Buffer
No information found.
Proprietary Electrolyte
No information available
Reproductive Toxicity
Sodium/Potassium Phosphate Buffer
No information found.
Proprietary Electrolyte
No information available
Teratogenic Effects
Sodium/Potassium Phosphate Buffer
No information found.
Proprietary Electrolyte
No information available
Routes of Entry
Sodium/Potassium Phosphate Buffer
No information found.
Proprietary Electrolyte
No information available
Target Organ Statement
Sodium/Potassium Phosphate Buffer
Persons with impaired kidney function may be more susceptible to the effects of the substance.
Proprietary Electrolyte
No information available
SECTION 12 - ECOLOGICAL INFOMATION
12.1 Toxicity
COMPONENT: Sodium/Potassium Phosphate Buffer
| Vertebrates | Invertebrates | Algae | Microorganisms | |
|---|---|---|---|---|
Aquatic Toxicity (ppm unless otherwise noted) | LC50 (96 hr, trout) >100mg/l | No data | NOEC (72hr) >100mg/l | NOEC (72 hrs) >1000mg/l |
| Birds | Arthropods | Plants | Microorganisms | |
|---|---|---|---|---|
Terrestrial Environment Toxicity (ppm unless otherwise noted) | No data | No data | No data | No data |
COMPONENT: Proprietary Electrolyte
| Vertebrates | Invertebrates | Algae | Microorganisms | |
|---|---|---|---|---|
Aquatic Toxicity (ppm unless otherwise noted) | LC50 (96hr bluegill) 5840mg/l | EC50 (daphnia, 48 hr) 874mg/l | EC50 2430 mg/L | NOEC 5000-8000mg/l |
| Birds | Arthropods | Plants | Microorganisms | |
|---|---|---|---|---|
Terrestrial Environment Toxicity (ppm unless otherwise noted) | LD50 (sparrow, 72hr) 3,000–3,500 mg/kg | NOEC (earthworm, 10wk) 60mM | IC50 (germination, 7days) 500-1890mg/kg soil | No data |
12.2 Persistence and Degradability
Sodium/Potassium Phosphate Buffer
No data
Proprietary Electrolyte
No data
12.3 Bioaccumulative Potential
Sodium/Potassium Phosphate Buffer
No data
Proprietary Electrolyte
No data
12.4 Mobility in Soil
Sodium/Potassium Phosphate Buffer
No data
Proprietary Electrolyte
No data
12.5 Results of PBT and vPvB Assessment
Sodium/Potassium Phosphate Buffer
does not apply
Proprietary Electrolyte
not PBT / vPvB
12.6 Other Adverse Effects
Sodium/Potassium Phosphate Buffer
None
Proprietary Electrolyte
None
SECTION 13 - DISPOSAL CONSIDERATIONS
13.1 Waste Treatment Methods
Offer surplus or non-recyclable product to licensed disposal company. Disposal is subject to user compliance with applicable law and product characteristics at time of disposal. Dispose of packaging as product.
SECTION 14 - TRANSPORT INFORMATION
| ADR/RID | IATA | IMO | DOT | |
|---|---|---|---|---|
| 14.1 UN Number | N.A. | N.A. | N.A. | N.A. |
| 14.2 Shipping Name | Not Regulated | Not Regulated | Not Regulated | Not Regulated |
| 14.3 Hazard Class | N.A. | N.A. | N.A. | N.A. |
| 14.4 Packing Group | N.A. | N.A. | N.A. | N.A. |
| 14.5 Environmental Hazards | N.A. | N.A. | Not regulated | N.A. |
| 14.6 Special Precautions | N.A. | N.A. | N.A. | N.A. |
SECTION 15 - REGULATORY INFORMATION
15.1 Safety, Health and Environmental Regulations/Legislation Specific for the Substance/Mixture
United States
TSCA Regulatory Statement
All intentional ingredients are listed on the TSCA Inventory.
SARA 311/312 Hazard Categories
| Component | Fire | Pressure | Reactivity | Acute | Chronic |
|---|---|---|---|---|---|
| Sodium/Potassium Phosphate Buffer | No | No | No | Yes | No |
| Proprietary Electrolyte | No | No | No | No | No |
Europe
EEC Regulatory
All intentional ingredients are listed on the European EINECS Inventory.
SECTION 16 - OTHER INFORMATION
Revisional Updates
4/26/2019 - Updated Section 1.4
5/29/2015 - Updated Sections 2.1 and 3.2
9/27/2013 - Released Version 1.0
NFPA Codes
Health 1 Flammability 0 Reactivity 0
Dangers
Sodium/Potassium Phosphate Buffer
None
Proprietary Electrolyte
None
MANUFACTURER DISCLAIMER: The information given herein is offered in good faith as accurate, but without guarantee. Conditions of the use and suitability of the product for particular uses are beyond our control. All risks of use of the product are therefore assumed by the user. Nothing is intended as a recommendation for uses which infringe valid patents or as extending license under valid patents. Appropriate warnings and safe handling procedures should be provided to handlers and users.