Version 3.0
Date revised: 4/26/2019
SAFETY DATA SHEET
Conforms to regulation (EC) no. EU 453/2010
SECTION 1 - IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
1.1 Product Identifier
1.2 Relevant Identified Uses of the Substance/Mixture and Uses Advised Against
Investigational research by professional users
1.3 Details of the Supplier of the Safety Data Sheet
| Manufacturer National Diagnostics 305 Patton Drive Atlanta, GA 30036 (404) 699-2121 (800) 526-3867 info@nationaldiagnostics.com |
1.4 Emergency Telephone Number
ChemTel Inc.
Contract number MIS8894340
1-800 255-3924 (United States, Canada, Puerto Rico & US Virgin Islands)
01-800-099-0731 (Mexico)
400-120-0751 (China)
000-800-100-4086 (India)
1-300-954-583 (Australia)
0-800-591-6042 (Brazil)
+1-813-255-3924 (All other regions)
SECTION 2 - HAZARDS IDENTIFICATION
2.1 Classification of the Substance or Mixture
Classification according to Regulation (EC) No. 1272/2008 [EU-GHS/CLP]
Serious Eye Damage/Eye Irritation (Category 2B)
2.2 Label Elements
| GHS Label Elements | ||
 |  | DANGER H225 - Highly flammable liquid and vapor. |
 | ||
2.3 Other Hazards
None found.
SECTION 3 - COMPOSITION/INFORMATION ON INGREDIENTS
3.1 Substance
Chemical Names/Description
N, N, N', N' - Tetramethylethylenediamine
Chemical Formula
C6H16N2
Component List
| Component | % Comp. | CAS # | EC # |
|---|---|---|---|
| Tetramethylethylenediamine | 100 | 110-18-9 | 203-744-6 |
SECTION 4 - FIRST AID MEASURES
4.1 Description of First Aid Measures
Inhalation
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician.
Ingestion
Do not induce vomiting. If swallowed and the person is conscious, immediately give large amounts of water. Get medical attention.
Skin
Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eyes
Immediately flush eyes with plenty of water for at least fifteen minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
4.2 Most Important Symptoms and Effects, Both Acute and Delayed
Inhalation
Burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea and vomiting. Inhalation may be fatal as a result of spasm inflammation and edema of the larynx and bronchi, chemical pneuomonitis and pulmonary edema.
Ingestion
Can cause sore throat, vomiting, diarrhea.
Skin
Redness, pain, and severe burns.
Eyes
Blurred vision, redness, and pain. Continuous exposure to low levels of vapor can cause a blurring of vision called Blue Haze.
4.3 Indication of Any Immediate Medical Attention and Special Treatment Needed
Unknown/not applicable
SECTION 5 - FIRE FIGHTING MEASURES
5.1 Extinguishing media
Dry powder, foam, carbon dioxide. (Water may be ineffective.)
5.2 Special Hazards Arising from the Substance/Mixture
Hazardous Combustion Products
Burning may produce carbon monoxide, carbon dioxide, nitrogen oxides.
Hazardous Decomposition Products
Burning may produce carbon monoxide, carbon dioxide, nitrogen oxides.
Hazardous Polymerization
Will not occur under normal conditions of use (See Sections 10.4 & 10.5).
5.3 Advice for Firefighters
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.
5.4 Further Information
No data available.
SECTION 6 - ACCIDENTAL RELEASE MEASURES
6.1 Personal Precautions
Wear appropriate protective equipment as specified in Section 8.
6.2 Environmental Precautions
Prevent discharge into the environment. Dike spills and stop leakage where practical. Do not allow material to enter drains.
6.3 Methods and Materials for Containment and Cleaning Up
Ventilate area. Remove all sources of ignition. Isolate hazard area. Use non-sparking tools and equipment. Collect liquid in an appropriate container or absorb with an inert material and place in a chemical waste container.
6.4 References to Other Sections
For disposal information see Section 13. For protective clothing and equipment see Section 8.
SECTION 7 - HANDLING AND STORAGE
7.1 Precautions for Safe Handling
Avoid contact and inhalation. Do not get in eyes, on skin, on clothing. Wash thoroughly after handling. Transfer methods should avoid static sparks. Use explosion proof ventilation.
7.2 Conditions for Safe Storage (including any incompatibles)
Store tightly capped under nitrogen gas at 4C. Isolate from incompatible materials (section 10).
Incompatibles
Acids, acid chlorides, acid anhydrides, strong oxidizing agents, carbon dioxide, copper and copper alloys.
7.3 Specific End Uses
Investigational research by professional users
SECTION 8 - EXPOSURE CONTROLS/PERSONAL PRECAUTIONS
8.1 Control Parameters
ACGIH Threshold Limit Value (TLV):
none established
OSHA Permissible Exposure Limit (PEL):
none established
8.2 Exposure Controls
Engineering Controls
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source.
Respiratory Protection
For conditions of use where exposure to the substance is apparent, consult an industrial hygienist. For emergencies, or instances where the exposure levels are not known, use a full-facepiece positive-pressure, air-supplied respirator.
Eye Protection
Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Skin Protection
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
9.1 Information on Basic Physical & Chemical Properties
| a. Appearance | Clear, colorless liquid | b. Odor | Strong amine odor |
| c. Odor Threshold | N.A. | d. pH | No information found |
| e. Melting/Freezing Point (oC) | -55 | f. Boiling point (oC) | 120-122 |
| g. Flash Point (oC) | 10 | h. Evaporation Rate | No information found |
| i. Flammability | Combustible | j. Upper/Lower Flammability or Explosive Limits | LEL, 0.98%; UEL, 9.08% |
| k. Vapor Pressure | 16 mm Hg @ 20C | l. Vapor Density (Air = 1) | No information found |
| m. Relative Density | 0.78 @ 20 C | n. Water Solubility | Soluble in water |
| o. Partition Coefficient n-octanol/water | N.A. | p. Autoignition Temperature (oC) | N.A. |
| q. Decomposition Temperature (oC) | N.A. | r. Viscosity | No data available. |
| s. Explosive Properties | Flammable vapors may create explosive condition | t. Oxidizing Properties | Not an oxidizer |
SECTION 10 - STABILITY AND REACTIVITY
10.1 Reactivity
Strong amine base- reacts violently with acids and oxidizing agents. Flammable vapors. Corrosive.
10.2 Chemical Stability
Stable under ordinary conditions of use and storage.
10.3 Possibility of Hazardous Reactions
Will not occur under normal conditions of use (See Sections 10.4 & 10.5).
10.4 Conditions to Avoid
Heat, flames, ignition sources and incompatibles.
10.5 Incompatible Materials
Acids, acid chlorides, acid anhydrides, strong oxidizing agents, carbon dioxide, copper and copper alloys.
10.6 Hazardous Decomposition Products
Burning may produce carbon monoxide, carbon dioxide, nitrogen oxides.
SECTION 11 - TOXICOLOGICAL INFORMATION
Product LD50 Values
Oral Rat LD50 (mg/kg)
268
Dermal Rabbit LD50 (mg/kg)
5390
Component Cancer List Status
| NTP Carcinogen | |||
| Known | Anticipated | IARC Category | |
|---|---|---|---|
| Tetramethylethylenediamine | No | No | None |
Potential Health Effects
Inhalation
Corrosive. Extremely destructive to tissues of the mucous membranes and upper respiratory tract.
Ingestion
Corrosive. Swallowing can cause severe burns of the mouth, throat, and stomach.
Skin
Corrosive. Can cause severe burns of the skin. May be absorbed through the skin with possible systemic effects.
Eyes
Corrosive. Contact can cause severe tissue burns.
Carcinogenicity
Not listed by NTP or IARC as a known or anticipated carcinogen.
Mutagenicity
Negative in the Ames Salmonella/Microsome Assay.
Reproductive Toxicity
No information found.
Teratogenic Effects
No information found.
Routes of Entry
Inhalation, ingestion or skin contact.
Target Organ Statement
Skin and eyes (irritation) are expected to be the primary target organs of this product. Continuous exposure to low levels of vapor can cause a blurring of vision called Blue Haze. This effect is temporary if the affected individual is removed to fresh air. Continuous exposure may have an effect on the nervous system.
SECTION 12 - ECOLOGICAL INFOMATION
12.1 Toxicity
| Vertebrates | Invertebrates | Algae | Microorganisms | |
|---|---|---|---|---|
Aquatic Toxicity (ppm unless otherwise noted) | No data | No data | No data | No data |
| Birds | Arthropods | Plants | Microorganisms | |
|---|---|---|---|---|
Terrestrial Environment Toxicity (ppm unless otherwise noted) | No data | No data | No data | No data |
12.2 Persistence and Degradability
No data
12.3 Bioaccumulative Potential
No data
12.4 Mobility in Soil
No data
12.5 Results of PBT and vPvB Assessment
No data
12.6 Other Adverse Effects
None
SECTION 13 - DISPOSAL CONSIDERATIONS
13.1 Waste Treatment Methods
Offer surplus or non-recyclable product to licensed disposal company. Disposal is subject to user compliance with applicable law and product characteristics at time of disposal. Dispose of packaging as product.
SECTION 14 - TRANSPORT INFORMATION
| ADR/RID | IATA | IMO | DOT | |
|---|---|---|---|---|
| 14.1 UN Number | 2372 | 2372 | 2372 | 2372 |
| 14.2 Shipping Name | 1,2 - Di - (dimethylamino) ethane | 1,2 - Di - (dimethylamino) ethane | 1,2 - Di - (dimethylamino) ethane | 1,2 - Di - (dimethylamino) ethane |
| 14.3 Hazard Class | 3 | 3 | 3 | 3 |
| 14.4 Packing Group | II | II | II | II |
| 14.5 Environmental Hazards | N.A. | N.A. | Not regulated | N.A. |
| 14.6 Special Precautions | N.A. | N.A. | N.A. | N.A. |
SECTION 15 - REGULATORY INFORMATION
15.1 Safety, Health and Environmental Regulations/Legislation Specific for the Substance/Mixture
United States
TSCA Regulatory Statement
All intentional ingredients are listed on the TSCA Inventory.
SARA 311/312 Hazard Categories
| Component | Fire | Pressure | Reactivity | Acute | Chronic |
|---|---|---|---|---|---|
| Tetramethylethylenediamine | Yes | No | No | Yes | No |
Europe
EEC Regulatory
All intentional ingredients are listed on the European EINECS Inventory.
SECTION 16 - OTHER INFORMATION
Revisional Updates
4/26/2019 - Updated Section 1.4
5/29/2015 - Updated Sections 2.1 and 3.1
7/23/2013 - Released Version 1.0
NFPA Codes
Health 3 Flammability 3 Reactivity 1
MANUFACTURER DISCLAIMER: The information given herein is offered in good faith as accurate, but without guarantee. Conditions of the use and suitability of the product for particular uses are beyond our control. All risks of use of the product are therefore assumed by the user. Nothing is intended as a recommendation for uses which infringe valid patents or as extending license under valid patents. Appropriate warnings and safe handling procedures should be provided to handlers and users.