Version 3.0
Date revised: 4/26/2019

SAFETY DATA SHEETNational Diagnostics

Conforms to regulation (EC) no. EU 453/2010

SECTION 1 - IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING

1.1 Product Identifier

Product Name: Formamide Product Number: EC-608

1.2 Relevant Identified Uses of the Substance/Mixture and Uses Advised Against

Investigational research by professional users

1.3 Details of the Supplier of the Safety Data Sheet

Manufacturer
National Diagnostics
305 Patton Drive
Atlanta, GA 30036
(404) 699-2121
(800) 526-3867
info@nationaldiagnostics.com

1.4 Emergency Telephone Number

ChemTel Inc.
Contract number MIS8894340
1-800 255-3924 (United States, Canada, Puerto Rico & US Virgin Islands)
01-800-099-0731 (Mexico)
400-120-0751 (China)
000-800-100-4086 (India)
1-300-954-583 (Australia)
0-800-591-6042 (Brazil)
+1-813-255-3924 (All other regions)

SECTION 2 - HAZARDS IDENTIFICATION

2.1 Classification of the Substance or Mixture

Classification according to Regulation (EC) No. 1272/2008 [EU-GHS/CLP]

H360 - Toxic to Reproduction (Category 1B)

2.2 Label Elements

GHS LABEL ELEMENTS AND CLASSIFICATION
GHS Label Elements
Human Health Hazard 

DANGER

H360 - May damage fertility or the unborn child.
P201 - Obtain special instructions before use.
P202 - Do not handle until all safety precautions have been read and understood.
P308+P313 - IF exposed or concerned: Call a POISON CENTER or doctor/physician.

  
  

2.3 Other Hazards

None found.

SECTION 3 - COMPOSITION/INFORMATION ON INGREDIENTS

3.1 Substance

Chemical Names/Description

Ultra-pure formamide.

Chemical Formula

CH3NO

Component List

Component % Comp. CAS # EC #
Formamide>99 75-12-7  200-842-0 


SECTION 4 - FIRST AID MEASURES

4.1 Description of First Aid Measures

Inhalation

Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician.

Ingestion

DO NOT INDUCE VOMITING. If swallowed and the person is conscious, immediately give large amounts of water. Get medical attention.

Skin

Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.

Eyes

Immediately flush eyes with plenty of water for at least fifteen minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.

4.2 Most Important Symptoms and Effects, Both Acute and Delayed

Inhalation

Symptoms may include coughing, shortness of breath. Excessive inhalation of vapor may cause symptoms that parallel ingestion, ranging from headache to unconsciousness, depending upon the duration and level of the exposure.

Ingestion

May cause headache, dizziness, nausea, vomiting, abdominal pain, and unconsciousness. May affect the repoductive system.

Skin

Symptoms include redness, itching, and pain. May be absorbed through the skin with symptoms parallel to ingestion.

Eyes

Redness and pain.

4.3 Indication of Any Immediate Medical Attention and Special Treatment Needed

Unknown/not applicable

SECTION 5 - FIRE FIGHTING MEASURES

5.1 Extinguishing media

Water spray, dry chemical, alcohol-resistant foam, or carbon dioxide. Water or foam may cause frothing.

5.2 Special Hazards Arising from the Substance/Mixture

Hazardous Combustion Products

Highly toxic gases may be involved in fires of this product.

Hazardous Decomposition Products

Burning may produce ammonia, carbon monoxide, carbon dioxide, nitrogen oxides. At boiling point: ammonia, carbon monoxide, and hydrogen cyanide.

Hazardous Polymerization

Will not occur under normal conditions of use (See Sections 10.4 & 10.5).

5.3 Advice for Firefighters

In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.

5.4 Further Information

No data available.

SECTION 6 - ACCIDENTAL RELEASE MEASURES

6.1 Personal Precautions

Wear appropriate protective equipment as specified in Section 8.

6.2 Environmental Precautions

Prevent discharge into the environment. Dike spills and stop leakage where practical. Do not allow material to enter drains.

6.3 Methods and Materials for Containment and Cleaning Up

Ventilate area. Cover with absorbent material (soda ash) to confine spill and sweep or shovel into container. Close container tightly. Avoid breathing vapors.

6.4 References to Other Sections

For disposal information see Section 13. For protective clothing and equipment see Section 8.

SECTION 7 - HANDLING AND STORAGE

7.1 Precautions for Safe Handling

Avoid contact and inhalation. Do not get in eyes, on skin, on clothing. Wash thoroughly after handling. Wear special protective equipment (Sec. 8) where exposures may exceed established levels.

7.2 Conditions for Safe Storage (including any incompatibles)

Keep in a tightly closed container, stored in a cooled, dry, ventilated area. Protect from physical damage. Isolate from incompatible materials (section 10).

Incompatibles

Acids, alkalines, iodine, pyridine, and sulfur trioxide. Copper, brass, lead, and rubber are attacked by formamide.

7.3 Specific End Uses

Investigational research by professional users

SECTION 8 - EXPOSURE CONTROLS/PERSONAL PRECAUTIONS

8.1 Control Parameters

ACGIH Threshold Limit Value (TLV):

10 ppm TWA

OSHA Permissible Exposure Limit (PEL):

None established

8.2 Exposure Controls

Engineering Controls

A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source.

Respiratory Protection

If the exposure limit is exceeded, wear a supplied air, full-facepiece respirator, airlined hood, or full-facepiece self-contained breathing apparatus.

Eye Protection

Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.

Skin Protection

Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.


SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES

9.1 Information on Basic Physical & Chemical Properties

a. AppearanceClear, colorless liquidb. OdorNone
c. Odor ThresholdN.A.d. pH7.1
e. Melting/Freezing Point (oC)2-3f. Boiling point (oC)210
g. Flash Point (oC)154h. Evaporation Rate< 1 (BuAc = 1)
i. FlammabilityN.A.j. Upper/Lower Flammability or Explosive LimitsNo Data
k. Vapor Pressure1 @ 71Cl. Vapor Density (Air = 1)1.55 (air = 1)
m. Relative Density1.13 @20Cn. Water SolubilityInfinitely soluble
o. Partition Coefficient n-octanol/waterlog Pow -0.82p. Autoignition Temperature (oC)No Data
q. Decomposition Temperature (oC)140Cr. ViscosityNo data available.
s. Explosive PropertiesN.A.t. Oxidizing PropertiesNot an oxidizer

SECTION 10 - STABILITY AND REACTIVITY

10.1 Reactivity

Stable under normal conditions of use.

10.2 Chemical Stability

Stable under ordinary conditions of use and storage. Absorbs moisture from the air.

10.3 Possibility of Hazardous Reactions

Will not occur under normal conditions of use (See Sections 10.4 & 10.5).

10.4 Conditions to Avoid

Heat, flames, ignition sources, and incompatibles.

10.5 Incompatible Materials

Acids, alkalines, iodine, pyridine, and sulfur trioxide. Copper, brass, lead, and rubber are attacked by formamide.

10.6 Hazardous Decomposition Products

Burning may produce ammonia, carbon monoxide, carbon dioxide, nitrogen oxides. At boiling point: ammonia, carbon monoxide, and hydrogen cyanide.

SECTION 11 - TOXICOLOGICAL INFORMATION

Product LD50 Values

Oral Rat LD50 (mg/kg)

5570

Dermal Rabbit LD50 (mg/kg)

No Data

Component Cancer List Status

 NTP Carcinogen 
 KnownAnticipatedIARC Category
FormamideNoNoNone

Potential Health Effects

Inhalation

Causes irritation to the respiratory tract.

Ingestion

Causes irritation to the gastrointestinal tract. Affects the central nervous system. May affect the reproductive system.

Skin

Causes irritation to the skin. May be absorbed through the skin.

Eyes

Causes irritation to the eyes.

Carcinogenicity

Not listed as a known or anticipated carcinogen by NTP or IARC.

Mutagenicity

No information found.

Reproductive Toxicity

May cause congenital malformation of the fetus.

Teratogenic Effects

May cause congenital malformation of the fetus.

Routes of Entry

Ingestion, inhalation, and absorption through the skin.

Target Organ Statement

No information found.

SECTION 12 - ECOLOGICAL INFOMATION

12.1 Toxicity

 VertebratesInvertebratesAlgaeMicroorganisms
Aquatic Toxicity
(ppm unless otherwise noted)
6569 @ 96 hrs>500 @ 48 hrs>500 @ 96 hrs>1000 @ 30min

 BirdsArthropodsPlantsMicroorganisms
Terrestrial Environment Toxicity
(ppm unless otherwise noted)
no datano datano datano data

12.2 Persistence and Degradability

Readily biodegradable (99% degradation at 28 days)

12.3 Bioaccumulative Potential

low expected bioaccumulation log BCF 0.5

12.4 Mobility in Soil

log Koc: 0.93

12.5 Results of PBT and vPvB Assessment

No Data

12.6 Other Adverse Effects

No data


SECTION 13 - DISPOSAL CONSIDERATIONS

13.1 Waste Treatment Methods

Offer surplus or non-recyclable product to licensed disposal company. Disposal is subject to user compliance with applicable law and product characteristics at time of disposal. Dispose of packaging as product.


SECTION 14 - TRANSPORT INFORMATION

  ADR/RID IATA IMO DOT
14.1 UN Number N.A.N.A.N.A.N.A.
14.2 Shipping NameNot regulatedNot regulatedNot regulatedNot regulated
14.3 Hazard ClassN.A.N.A.N.A.N.A.
14.4 Packing GroupN.A.N.A.N.A.N.A.
14.5 Environmental HazardsN.A.N.A.Not regulatedN.A.
14.6 Special PrecautionsN.A.N.A.N.A.N.A.

SECTION 15 - REGULATORY INFORMATION

15.1 Safety, Health and Environmental Regulations/Legislation Specific for the Substance/Mixture

United States

TSCA Regulatory Statement

All intentional ingredients are listed on the TSCA Inventory.

SARA 311/312 Hazard Categories
ComponentFirePressureReactivityAcuteChronic
FormamideNoNoNoYesYes

Europe

EEC Regulatory

All intentional ingredients are listed on the European EINECS Inventory.

SECTION 16 - OTHER INFORMATION

Revisional Updates

4/26/2019 - Updated Section 1.4
5/29/2015 - Updated Sections 2.1 and 3.1
8/13/2013 - Released Version 1.0

NFPA Codes

Health 2   Flammability 1  Reactivity 0

MANUFACTURER DISCLAIMER: The information given herein is offered in good faith as accurate, but without guarantee. Conditions of the use and suitability of the product for particular uses are beyond our control. All risks of use of the product are therefore assumed by the user. Nothing is intended as a recommendation for uses which infringe valid patents or as extending license under valid patents. Appropriate warnings and safe handling procedures should be provided to handlers and users.