Version 3.0
Date revised: 4/26/2019
SAFETY DATA SHEET
Conforms to regulation (EC) no. EU 453/2010
SECTION 1 - IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
1.1 Product Identifier
1.2 Relevant Identified Uses of the Substance/Mixture and Uses Advised Against
Investigational research by professional users
1.3 Details of the Supplier of the Safety Data Sheet
| Manufacturer National Diagnostics 305 Patton Drive Atlanta, GA 30036 (404) 699-2121 (800) 526-3867 info@nationaldiagnostics.com |
1.4 Emergency Telephone Number
ChemTel Inc.
Contract number MIS8894340
1-800 255-3924 (United States, Canada, Puerto Rico & US Virgin Islands)
01-800-099-0731 (Mexico)
400-120-0751 (China)
000-800-100-4086 (India)
1-300-954-583 (Australia)
0-800-591-6042 (Brazil)
+1-813-255-3924 (All other regions)
SECTION 2 - HAZARDS IDENTIFICATION
2.1 Classification of the Substance or Mixture
Classification according to Regulation (EC) No. 1272/2008 [EU-GHS/CLP]
H226 - Flammable Liquids (Category 3)
H312 - Acute Toxicity-Dermal (Category 4)
H315 - Skin Corrosion/Irritation (Category 2)
H332 - Acute Toxicity-Inhalation (Category 4)
2.2 Label Elements
| GHS Label Elements | ||
 |  | WARNING H226 - Flammable liquid and vapor. |
2.3 Other Hazards
None found.
SECTION 3 - COMPOSITION/INFORMATION ON INGREDIENTS
3.2 Mixture
Chemical Names/Description
Aromatic hydrocarbons.
Component List
| Component | % Comp. | CAS # | EC # | 1278/2008 Classification |
|---|---|---|---|---|
| Xylene | 30 - 50 | 1330-20-7 | 215-535-7 | H226, H312, H315, H332 |
| Nonhazardous Component | 40 - 60 | N.A. |
SECTION 4 - FIRST AID MEASURES
4.1 Description of First Aid Measures
Inhalation
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician.
Ingestion
Do not induce vomiting. If swallowed and the person is conscious, immediately give large amounts of water. Get medical attention.
Skin
Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eyes
Immediately flush eyes with plenty of water for at least fifteen minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
4.2 Most Important Symptoms and Effects, Both Acute and Delayed
Inhalation
Xylene:
Inhalation of high concentrations may result in nausea, vomiting, headache, ringing in the ears, and severe breathing difficulties which may be delayed in onset. Substernal pain, cough, and hoarseness are also reported. Symptoms of central nervous system depression or effects which may occur can include headache, excitation, euphoria, dizziness, incoordination, drowsiness, light-headedness, blurred vision, fatigue, tremors, convulsions, loss of consciousness, coma, respiratory arrest and death, depending on the concentration and duration of exposure.
Nonhazardous Component:
No information found.
Ingestion
Xylene:
Salivation, pain, nausea, vomiting and diarrhea. Exposure may also cause central nervous system symptoms similar to those listed under Inhalation.
Nonhazardous Component:
No information found.
Skin
Xylene:
Reddening, itching, and inflammation. Repeated or prolonged contact may result in drying, reddening, itching, pain, inflammation, cracking and possible secondary infection with tissue damage.
Nonhazardous Component:
No information found.
Eyes
Xylene:
Pain, tears, burns, sensitivity to light, swelling and possible corneal damage. Prolonged or repeated exposure may cause irritation and conjunctivitis.
Nonhazardous Component:
No information found.
4.3 Indication of Any Immediate Medical Attention and Special Treatment Needed
Unknown/not applicable
SECTION 5 - FIRE FIGHTING MEASURES
5.1 Extinguishing media
Dry powder, foam, carbon dioxide. Water spray may be used to keep fire exposed containers cool, dilute spills to nonflammable mixtures, protect personnel attempting to stop leak and disperse vapors.
5.2 Special Hazards Arising from the Substance/Mixture
Hazardous Combustion Products
Involvement in a fire causes formation of carbon monoxide and unidentified organic components.
Hazardous Decomposition Products
Involvement in fire causes formation of carbon monoxide and unidentified organic compounds.
Hazardous Polymerization
Will not occur under normal conditions of use (See Sections 10.4 & 10.5).
5.3 Advice for Firefighters
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.
5.4 Further Information
No data available.
SECTION 6 - ACCIDENTAL RELEASE MEASURES
6.1 Personal Precautions
Wear appropriate protective equipment as specified in Section 8.
6.2 Environmental Precautions
Prevent discharge into the environment. Dike spills and stop leakage where practical. Do not allow material to enter drains.
6.3 Methods and Materials for Containment and Cleaning Up
Ventilate area of leak or spill. Remove all sources of ignition. Isolate hazard area. Collect liquid in an appropriate container or absorb with an inert material and place in a chemical waste container. Do not flush to sewer!
6.4 References to Other Sections
For disposal information see Section 13. For protective clothing and equipment see Section 8.
SECTION 7 - HANDLING AND STORAGE
7.1 Precautions for Safe Handling
Avoid contact and inhalation. Do not get in eyes, on skin, on clothing. Wash thoroughly after handling. Transfer methods should avoid static sparks. Use explosion proof ventilation.
7.2 Conditions for Safe Storage (including any incompatibles)
Keep in a tightly closed container, stored in a cooled, dry, ventilated area away from sources of heat or ignition. Protect from physical damage. Isolate from incompatible materials (section 10).
Incompatibles
Xylene:
Strong oxidizing agents and strong acids.
Nonhazardous Component:
No information found.
7.3 Specific End Uses
Investigational research by professional users
SECTION 8 - EXPOSURE CONTROLS/PERSONAL PRECAUTIONS
8.1 Control Parameters
Component: Xylene
ACGIH Threshold Limit Value (TLV):
100 ppm
OSHA Permissable Exposure Limit (PEL):
100 ppm
Component: Nonhazardous Component
ACGIH Threshold Limit Value (TLV):
None established
OSHA Permissable Exposure Limit (PEL):
None established
8.2 Exposure Controls
Engineering Controls
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source.
Respiratory Protection
If the exposure limit is exceeded, wear a supplied air, full-facepiece respirator, airlined hood, or full-facepiece self-contained breathing apparatus.
Eye Protection
Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Skin Protection
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
9.1 Information on Basic Physical & Chemical Properties
| a. Appearance | Clear, colorless liquid | b. Odor | Slight sweet odor |
| c. Odor Threshold | N.A. | d. pH | Not Applicable |
| e. Melting/Freezing Point (oC) | -25 | f. Boiling point (oC) | 137-140 |
| g. Flash Point (oC) | 29 | h. Evaporation Rate | 0.7 (Bu Acetate = 1) |
| i. Flammability | Combustible | j. Upper/Lower Flammability or Explosive Limits | LEL: 1.0%; UEL: 7.0% |
| k. Vapor Pressure | 4 @ 25 C | l. Vapor Density (Air = 1) | 4.8 |
| m. Relative Density | 0.95 | n. Water Solubility | Insoluble |
| o. Partition Coefficient n-octanol/water | Mixture | p. Autoignition Temperature (oC) | 464 |
| q. Decomposition Temperature (oC) | Not applicable. | r. Viscosity | No data available. |
| s. Explosive Properties | N.A. | t. Oxidizing Properties | N.A. |
SECTION 10 - STABILITY AND REACTIVITY
10.1 Reactivity
Not reactive under normal conditions of use and storage.
10.2 Chemical Stability
Stable under ordinary conditions of use and storage.
10.3 Possibility of Hazardous Reactions
Will not occur under normal conditions of use (See Sections 10.4 & 10.5).
10.4 Conditions to Avoid
Heat, flames, ignition sources, and incompatibles.
10.5 Incompatible Materials
Xylene:
Strong oxidizing agents and strong acids.
Nonhazardous Component:
No information found.
10.6 Hazardous Decomposition Products
Involvement in fire causes formation of carbon monoxide and unidentified organic compounds.
SECTION 11 - TOXICOLOGICAL INFORMATION
Product LD50 Values
Oral Rat LD50 (mg/kg)
10750
Dermal Rabbit LD50 (mg/kg)
4250
Component Cancer List Status
| NTP Carcinogen | |||
| Known | Anticipated | IARC Category | |
|---|---|---|---|
| Xylene | No | No | 3 |
| Nonhazardous Component | No | No | None |
Potential Health Effects
Inhalation
Xylene
Inhalation of vapors may be irritating to the nose and throat. High vapor concentrations are anesthetic and central nervous system depressants.
Nonhazardous Component
No information found.
Ingestion
Xylene
May cause irritation of the mouth, throat, and gastrointestinal tract. Aspiration into lungs may cause chemical pneumonia and lung damage.
Nonhazardous Component
No information found.
Skin
Xylene
Skin contact results in loss of natural oils and often results in a characteristic dermatitis. May be absorbed through the skin.
Nonhazardous Component
No information found.
Eyes
Xylene
Vapors cause eye irritation. Splashes cause severe irritation, possible corneal burns and eye damage.
Nonhazardous Component
No information found.
Carcinogenicity
Xylene
IARC has determined that there is inadequate evidence to assign the carcinogenicity of xylene in humans and in experimental animals (IARC Class 3).
Nonhazardous Component
No information found.
Mutagenicity
Xylene
Has been shown to be positive in mutagenicity assays.
Nonhazardous Component
No information found.
Reproductive Toxicity
Xylene
May cause adverse reproductive and/or developmental effects. Pregnant women may be at an increased risk from exposure. Consumption of alcoholic beverages may enhance toxic effects.
Nonhazardous Component
No information found.
Teratogenic Effects
Xylene
May cause teratogenic effects.
Nonhazardous Component
No information found.
Routes of Entry
Xylene
Inhalation, ingestion, and skin contact.
Nonhazardous Component
No information found.
Target Organ Statement
Xylene
Pre-existing medical conditions which may be aggravated by exposure include disorders of the skin, eye, heart, kidney, liver, blood, respiratory system, neurological and hemopoietic organs.
Nonhazardous Component
No information found.
SECTION 12 - ECOLOGICAL INFOMATION
12.1 Toxicity
COMPONENT: Xylene
| Vertebrates | Invertebrates | Algae | Microorganisms | |
|---|---|---|---|---|
Aquatic Toxicity (ppm unless otherwise noted) | LC50 (96 hr, Salmo gairdneri) 2.6 mg/l | IC50 (Daphnia magna) 1 mg/l. | EC50 2.2 mg/l | IC50 (24hr) 96mg/l |
| Birds | Arthropods | Plants | Microorganisms | |
|---|---|---|---|---|
Terrestrial Environment Toxicity (ppm unless otherwise noted) | No data | No data | No data | IC50 (10hrs) 0.22g/g soil |
COMPONENT: Nonhazardous Component
| Vertebrates | Invertebrates | Algae | Microorganisms | |
|---|---|---|---|---|
Aquatic Toxicity (ppm unless otherwise noted) | No data | No data | No data | No data |
| Birds | Arthropods | Plants | Microorganisms | |
|---|---|---|---|---|
Terrestrial Environment Toxicity (ppm unless otherwise noted) | No data | No data | No data | No data |
12.2 Persistence and Degradability
Xylene
Readily biodegradable, >85% elimination in 28 days
Nonhazardous Component
No data
12.3 Bioaccumulative Potential
Xylene
BCF 5-15
Nonhazardous Component
No data
12.4 Mobility in Soil
Xylene
log Koc 2.73
Nonhazardous Component
No data
12.5 Results of PBT and vPvB Assessment
Xylene
not PBT / vPvB
Nonhazardous Component
No data
12.6 Other Adverse Effects
Xylene
None
Nonhazardous Component
None
SECTION 13 - DISPOSAL CONSIDERATIONS
13.1 Waste Treatment Methods
Offer surplus or non-recyclable product to licensed disposal company. Disposal is subject to user compliance with applicable law and product characteristics at time of disposal. Dispose of packaging as product.
SECTION 14 - TRANSPORT INFORMATION
| ADR/RID | IATA | IMO | DOT | |
|---|---|---|---|---|
| 14.1 UN Number | 1307 | 1307 | 1307 | 1307 |
| 14.2 Shipping Name | Xylenes | Xylenes | Xylenes | Xylenes |
| 14.3 Hazard Class | 3 | 3 | 3 | 3 |
| 14.4 Packing Group | III | III | III | III |
| 14.5 Environmental Hazards | N.A. | N.A. | Not regulated | N.A. |
| 14.6 Special Precautions | N.A. | N.A. | N.A. | N.A. |
SECTION 15 - REGULATORY INFORMATION
15.1 Safety, Health and Environmental Regulations/Legislation Specific for the Substance/Mixture
United States
TSCA Regulatory Statement
All intentional ingredients are listed on the TSCA Inventory.
SARA 311/312 Hazard Categories
| Component | Fire | Pressure | Reactivity | Acute | Chronic |
|---|---|---|---|---|---|
| Xylene | Yes | No | No | Yes | Yes |
| Nonhazardous Component | No | No | No | No | No |
Europe
EEC Regulatory
All intentional ingredients are listed on the European EINECS Inventory.
SECTION 16 - OTHER INFORMATION
Revisional Updates
4/26/2019 - Updated Section 1.4
5/29/2015 - Updated Sections 2.1 and 3.2
8/29/2013 - Released Version 1.0
NFPA Codes
Health 2 Flammability 3 Reactivity 0
Dangers
Xylene
H226 - Flammable liquid and vapor.
H312 - Harmful in contact with skin.
H315 - Causes skin irritation.
H332 - Harmful if inhaled.
Nonhazardous Component
None
MANUFACTURER DISCLAIMER: The information given herein is offered in good faith as accurate, but without guarantee. Conditions of the use and suitability of the product for particular uses are beyond our control. All risks of use of the product are therefore assumed by the user. Nothing is intended as a recommendation for uses which infringe valid patents or as extending license under valid patents. Appropriate warnings and safe handling procedures should be provided to handlers and users.